Research


Dr. Mercola on the Dangers of Fluoridated Toothpaste

Dr. Mercola on the Dangers of Fluoridated Toothpaste

Regular readers of our website, along with our patients, are well aware of the dangers of ingested fluoride. Less frequently we discuss the downsides to topical fluoride (like what you find in most toothpaste). Research that’s been done is spotty at best, but for the most part, research has shown that large doses of topical fluoride MAY have a positive effect on decay. Of course,...

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Effects of Metals on the Nervous System of Humans and Animals

Several metals have toxic actions on nerve cells and neurobehavorial functioning. These toxic actions can be expressed either as developmental effects or as an increased risk of neurodegenerative diseases in old age. The major metals causing neurobehavioral effects after developmental exposure are lead and methylmercury. Lead exposure in young children results in a permanent loss of IQ of approximately 5 to 7 IQ points, and...

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Metals and Trace Elements in Plasma and Cerebrospinal Fluid in Normal Aging and Alzheimer’s Disease

Cerebro-spinal fluid (CSF) and blood levels of aluminium, cadmium, calcium, copper, lead, magnesium, and mercury were studied in 24 subjects with dementia of the Alzheimer type (DAT) and in 28 healthy volunteers. Furthermore, arsenic, bromine, chrome, iron, manganese, nickel, rubidium, selenium, strontium, and zinc were measured only in blood. There were significant changes in the DAT group when compared to the controls. The plasma levels...

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Cysteine Metabolism and Metal Toxicity

Chronic, low level exposure to toxic metals is an increasing global problem. The symptoms associated with the slow accumulation of toxic metals are multiple and rather nondescript, and overt expression of toxic effects may not appear until later in life. The sulfhydryl-reactive metals (mercury, cadmium, lead, arsenic) are particularly insidious and can affect a vast array of biochemical and nutritional processes. The primary mechanisms by...

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Molecular Mechanisms of Metal Toxicity and Carcinogenesis

Many metals and metal-containing compounds have been identified to be potent mutagens and carcinogens. Recently, a new sub-discipline of molecular toxicology and carcinogenesis has been developed. The combination of newly developed molecular techniques and free radical approach makes it possible to insightfully examine metal-induced carcinogenesis in precise molecular terms so that intricate biological interrelationships can be elucidated. In consideration of the increased amount of new...

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